Research Output per Year
Research Output per Year
Overview
Personal Profile
Chao Wu's research includes evaluation of the thermodynamic feasibility and metabolic robustness of engineered metabolic pathways, which is used to identify potential metabolic bottlenecks and flux control sites for enhanced biofuel productivity. The computational tools he develops help to decipher the intracellular fluxomics in response to genetic modifications and growth environment perturbations. Parts of his ongoing research develop metabolic models and estimate cellular resource allocation in response to harsh bioproduction conditions during the production of biofuels and bioproducts. In addition, he also works on the automation of techno-economic analysis of biofuel production pathways leveraging machine learning methods.
Research Interests
Metabolic modeling
Metabolic flux analysis and computational tool development
Metabolic robustness analysis of biosystems
Machine learning and deep learning in systems biology
Biochemical process simulation and optimization
Bioinformatics and computational biology
Professional Experience
Postdoctoral Researcher, NREL (2018–2021)
Senior Bioinformatics Engineer, Megagenomics Co., Ltd. (2016–2018)
Education/Academic Qualification
Bachelor, Kinesiology, Beijing Sport University
PhD, Biology, Tsinghua University
Fingerprint
Dive into the research topics where Chao Wu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and Top Research Areas From the Past 5 Years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
-
Machine Learning-Enabled Techno-Economic Uncertainty Analysis of Sustainable Aviation Fuel Production Pathways: Article No. 100650
Wu, C., Wang, Y. & Tao, L., 2024, In: Chemical Engineering Journal Advances. 20, 10 p.Research output: Contribution to journal › Article › peer-review
-
4 Scopus Citations
-
FreeFlux: A Python Package for Time-Efficient Isotopically Nonstationary Metabolic Flux Analysis
Wu, C., Guarnieri, M. & Xiong, W., 2023, In: ACS Synthetic Biology. 12, 9, p. 2707-2714 8 p.Research output: Contribution to journal › Article › peer-review
4 Scopus Citations -
Thermodynamic and Kinetic Modeling Directs Pathway Optimization for Isopropanol Production in a Gas-Fermenting Bacterium
Lo, J., Wu, C., Humphreys, J., Yang, B., Jiang, Z., Wang, X., Maness, P., Tsesmetzis, N. & Xiong, W., 2023, In: Journal of Bacteriology. 8, 2, 15 p.Research output: Contribution to journal › Article › peer-review
-
Acetyl-CoA Synthesis Through a Bicyclic Carbon-Fixing Pathway in Gas-Fermenting Bacteria
Wu, C., Lo, J., Urban, C., Gao, X., Yang, B., Humphreys, J., Shinde, S., Wang, X., Chou, K., Maness, P., Tsesmetzis, N., Parker, D. & Xiong, W., 2022, In: Nature Synthesis. 1, 8, p. 615-625 11 p.Research output: Contribution to journal › Article › peer-review
21 Scopus Citations
Awards and Honors
-
-
-
-
NREL Director’s Award
Choi, H. (Recipient), Walzberg, J. (Recipient), Arellano Trevino, M. (Recipient), Shankari, K. (Recipient), McNeary, W. (Recipient), Choi, H. (Recipient) & Wu, C. (Recipient), 2021
Prize: Honorary award
-