Research Output per Year
Research Output per Year
Overview
Research Interests
Development of thermophilic bacteria for improved biomass deconstruction
Biomass degrading mechanisms of thermophilic bacteria
Metabolic modeling and pathway engineering in microbes for upgrading sugar to fuels and high value chemicals
Metabolic enzyme characterization, modeling, and engineering (thermostability, cofactor specificity, binding, rate limiting step)
Characterization, modeling, and engineering of biomass degrading enzymes from mesophilic and thermophilic bacteria
Quantum chemical calculations for the study of thermochemical properties and processes
Molecular dynamics
Quantum chemistry
Computational modeling
Computer software development (for applications in molecular dynamics [MD] and quantum mechanics [QM] calculations)
Protein purification
Protein characterization
Metabolic modeling
Professional Experience
Senior Research Scientist, National Renewable Energy Laboratory (NREL), 2010–present
Research Scientist, NREL, 2008–2010
Research Associate, Scripps Research Institute, Department of Molecular Biology, 2006–2008
Graduate Research Assistant, University of Texas, Department of Chemistry and Biochemistry, 2001–2006
Visiting Research Fellow, Universitt Mainz, Germany, Institut für Physikalische Chemie, 2004 and 2005
IMCC exchange fellow, Université de Lille I/ University of Texas, Austin, 2001
Education/Academic Qualification
Mathématiques Speciales, Lycée Faidherbe
Mathématiques Superieures, Lycée Faidherbe
PhD, Chemical Physics, University of Texas
Bachelor, Physics (with honors), minors in Mathematics and Chemistry, Université de Lille
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Collaborations and Top Research Areas From the Past 5 Years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Atomistic, Macromolecular Model of the Populus Secondary Cell Wall Informed by Solid-State NMR: Article No. eadi7965
Addison, B., Bu, L., Bharadwaj, V., Crowley, M., Harmon-Ware, A., Crowley, M., Bomble, Y. & Ciesielski, P., 2024, In: Science Advances. 10, 1, 13 p.Research output: Contribution to journal › Article › peer-review
14 Scopus Citations -
Cell-Free Systems Biology: Characterizing Central Metabolism of Clostridium thermocellum with a Three-Enzyme Cascade Reaction
Jilani, S. B., Alahuhta, M., Bomble, Y. & Olson, D., 2024, In: ACS Synthetic Biology. 13, 11, p. 3587-3599 13 p.Research output: Contribution to journal › Article › peer-review
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Long-Term Stability of Nicotinamide Cofactors in Common Aqueous Buffers: Implications for Cell-Free Biocatalysis: Article No. 5453
Wolfe, K., Alahuhta, M., Himmel, M., Bomble, Y., Jennings, G. K. & Cliffel, D., 2024, In: Molecules. 29, 22, 11 p.Research output: Contribution to journal › Article › peer-review
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Streamlining Heterologous Expression of Top Carbonic Anhydrases in Escherichia coli: Bioinformatic and Experimental Approaches: Article No. 190
Wei, H., Lunin, V., Alahuhta, M., Himmel, M., Huang, S., Bomble, Y. & Zhang, M., 2024, In: Microbial Cell Factories.Research output: Contribution to journal › Article › peer-review
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The Role of AdhE on Ethanol Tolerance and Production in Clostridium Thermocellum: Article No. 107559
Pech-Canul, A., Hammer, S., Ziegler, S., Richardson, I., Sharma, B., Maloney, M., Bomble, Y., Lynd, L. & Olson, D., 2024, In: Journal of Biological Chemistry. 300, 8, 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus Citations