ABF Past Accomplishments - TEA/LCA

Bruno Klein, Pahola Thathiana Benavides

Research output: NRELPresentation


The Integrated Analysis task in the Agile BioFoundry (ABF) conducts techno-economic analysis (TEA) and life cycle assessment (LCA) to quantify the economics and environmental impacts of bioprocesses under development. The team from Argonne National Laboratory (ANL) and the National Renewable Energy Laboratory (NREL) develops TEA and LCA models of selected compound targets and hosts of interest to the ABF in an effort to provide an analysis-based foundation to the R&D. To date, the Integrated Analysis task has performed process modeling and analyses on multiple pairings of bioproducts and hosts, centered around major metabolic "beachheads" and "exemplar" molecules chosen for each of the metabolic pathways of interest. This presentation provides an overview of the approach used for TEA and LCA in the ABF and of the progress, outcomes, and impacts of TEA and LCA to support ABF goals, with a focus towards developing bio-based products that are both environmentally and economically viable.
Original languageAmerican English
Number of pages23
StatePublished - 2023

Publication series

NamePresented at the 2023 U.S. Department of Energy's Bioenergy Technologies Office (BETO) Project Peer Review, 3-7 April 2023, Denver, Colorado

NREL Publication Number

  • NREL/PR-5100-85566


  • bioproduct
  • biorefinery
  • fermentation
  • greenhouse gas emissions
  • LCA
  • metabolic pathway
  • minimum selling price
  • process simulation
  • TEA


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