Biological Production of Organic Compounds

Jianping Yu (Inventor), Pin-Ching Maness (Inventor), Michael Seibert (Inventor), Troy Paddock (Inventor), Damian Carrieri (Inventor), Bo Wang (Inventor)

Research output: Patent


Methods of producing ethylene oxide and ethylene glycol are disclosed herein. Ethylene produced by cyanobacteria engineered to express ethylene-forming enzymes may be converted to ethylene oxide by bacteria engineered to express a monooxygenase enzyme. Ethylene oxide may be converted to ethylene glycol by exposure to an acidic solution. The methods may be performed in a bioreactor.
Original languageAmerican English
Patent number9,914,947
Filing date13/03/18
StatePublished - 2018

NREL Publication Number

  • NREL/PT-2700-71176


  • bioreactor
  • cyanobacteria
  • engineered
  • ethylene glycol
  • ethylene oxide
  • ethylene-forming enzymes
  • monooxygenase enzyme


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