Bypassing Fast Time Scales of the Hodgkin-Huxley Neuron Model via a Thresholded Hard Reset

Research output: NLRTechnical Report

Abstract

We propose a modification to the Hodgkin-Huxley model to reduce the numerical stiffness of the equations by introducing an explicit voltage threshold. When this threshold is crossed, the voltage and the gating variables are reset to constant values. It is found that, for all of the current stimuli considered, the proposed model accurately reproduces the behavior of the baseline Hodgkin-Huxley model while bypassing the fast dynamics of spiking. Specifically, the model accurately reproduces the spike times and, between spikes, the time courses of the membrane potential and gating variables.
Original languageAmerican English
Number of pages14
StatePublished - 2025

NLR Publication Number

  • NREL/TP-2C00-94669

Keywords

  • biofaithful
  • biophysical
  • neuromorphic
  • spiking

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