Chapter 13: Software and Methods for Computational Flux Balance Analysis

Peter St. John, Yannick Bomble

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


As genetic engineering of organisms has grown easier and more precise, computational modeling of metabolic systems has played an increasingly important role in both guiding experimental interventions and in understanding the results of metabolic perturbations.

Original languageAmerican English
Title of host publicationMetabolic Pathway Engineering
Subtitle of host publicationMethods in Molecular Biology, Volume 2096
EditorsM. E. Himmel, Y. J. Bomble
PublisherHumana Press Inc.
Number of pages13
StatePublished - 2020

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Bibliographical note

Publisher Copyright:
© Springer Science+Business Media, LLC, part of Springer Nature 2020.

NREL Publication Number

  • NREL/CH-2700-74954


  • Computational Model
  • Constraint-based reconstruction and analysis
  • Flux Balance Analysis
  • Metabolic networks
  • Strain design


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