Chimeric Enzymes for Conversion of Lignin-Derived Chemicals

Christopher Johnson; Gregg Beckham; Jeffrey Linger; Ellen Neidle; Mark Eiteman; Melissa Tumen-Velasquaz; Alaa Mahmoud Ahmed

Chimeric Enzymes for Conversion of Lignin-Derived Chemicals

Christopher Johnson (Inventor), Gregg Beckham (Inventor), Jeffrey Linger (Inventor), Ellen Neidle (Inventor), Mark Eiteman (Inventor), Melissa Tumen-Velasquaz (Inventor), Alaa Mahmoud Ahmed (Inventor)

University of Georgia

Research output: Patent

Abstract

Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and optimizing genetic regions.

Original language	American English
Patent number	10,087,425 B2
Filing date	2/10/18
State	Published - 2018

NREL Publication Number

NREL/PT-5100-72565

Keywords

aromatic substrates
catechol
dealkylation
enzymes
feedstocks
guaethol
guaiacol
lignin
pyrolysis

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Cite this

@misc{c97c6f90765447cb829afc556578380e,

title = "Chimeric Enzymes for Conversion of Lignin-Derived Chemicals",

abstract = "Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and optimizing genetic regions.",

keywords = "aromatic substrates, catechol, dealkylation, enzymes, feedstocks, guaethol, guaiacol, lignin, pyrolysis",

author = "Christopher Johnson and Gregg Beckham and Jeffrey Linger and Ellen Neidle and Mark Eiteman and Melissa Tumen-Velasquaz and {Mahmoud Ahmed}, Alaa",

year = "2018",

language = "American English",

type = "Patent",

note = "10,087,425 B2",

}

TY - PAT

T1 - Chimeric Enzymes for Conversion of Lignin-Derived Chemicals

AU - Johnson, Christopher

AU - Beckham, Gregg

AU - Linger, Jeffrey

AU - Neidle, Ellen

AU - Eiteman, Mark

AU - Tumen-Velasquaz, Melissa

AU - Mahmoud Ahmed, Alaa

PY - 2018

Y1 - 2018

N2 - Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and optimizing genetic regions.

AB - Disclosed herein are enzymes useful for the dealkylation of aromatic substrates, including the conversion of guaiacol or guaethol to catechol. Methods of converting aromatic substrates found in lignin-based feedstocks such as pyrolysis oil into products such as catechol are also disclosed. Also presented herein are methods for rapidly evolving and optimizing genetic regions.

KW - aromatic substrates

KW - catechol

KW - dealkylation

KW - enzymes

KW - feedstocks

KW - guaethol

KW - guaiacol

KW - lignin

KW - pyrolysis

M3 - Patent

M1 - 10,087,425 B2

Y2 - 2018/10/02

ER -

Chimeric Enzymes for Conversion of Lignin-Derived Chemicals

Abstract

NREL Publication Number

Keywords

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