Conversion of S-Lignin Compounds to Useful Intermediates

Gregg Beckham (Inventor), Christopher Johnson (Inventor), Sandra Notonier (Inventor)

Research output: Patent


The present disclosure relates to a genetically modified microbial cell that includes a genetic modification resulting in the expression of a vanillate demethylase, where the microbial cell is capable of metabolizing at least one S-lignin decomposition molecule including at least one of syringate and/or 3-O-methyl gallate, and the genetically modified microbial cell is capable of producing gallate. In some embodiments of the present disclosure, the vanillate demethylase may include VanAB.
Original languageAmerican English
Patent number11,136,601 B2
Filing date5/10/21
StatePublished - 2021

NREL Publication Number

  • NREL/PT-2A00-81180


  • 3-O-methyl gallate
  • molecule of syringate
  • S-lignin decomposition
  • vanillate demethylase


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