TY - JOUR
T1 - Energy-Resolved Mass Spectrometry as a Tool for Identification of Lignin Depolymerization Products
T2 - Article No. e202201441
AU - Dong, Xueming
AU - Mayes, Heather
AU - Morreel, Kris
AU - Katahira, Rui
AU - Li, Yanding
AU - Ralph, John
AU - Black, Brenna
AU - Beckham, Gregg
PY - 2023
Y1 - 2023
N2 - Lignin is the largest source of bio-based aromatic compounds in nature, and its valorization is essential to the sustainability of lignocellulosic biorefining. Characterizing lignin-derived compounds remains challenging due to the heterogeneity of this biopolymer. Tandem mass spectrometry is a promising tool for lignin structural analytics, as fragmentation patterns of model compounds can be extrapolated to identify characteristic moieties in complex samples. This work extends previous resonance excitation type collision-induced dissociation (CID) methods that identified lignin oligomers containing ..beta..-..omicron..-4, ..beta..-5, and ..beta..-..beta.. bonds, to also identify characteristics of 5-5, ..beta..-1, and 4-..omicron..-5 dimers, enabled by quadrupole time-of-flight (QTOF) CID with energy-resolved mass spectrometry (ERMS). Overall, QTOFERMS offers in-depth structural information and could ultimately contribute to tools for high-throughput lignin dimer identification.
AB - Lignin is the largest source of bio-based aromatic compounds in nature, and its valorization is essential to the sustainability of lignocellulosic biorefining. Characterizing lignin-derived compounds remains challenging due to the heterogeneity of this biopolymer. Tandem mass spectrometry is a promising tool for lignin structural analytics, as fragmentation patterns of model compounds can be extrapolated to identify characteristic moieties in complex samples. This work extends previous resonance excitation type collision-induced dissociation (CID) methods that identified lignin oligomers containing ..beta..-..omicron..-4, ..beta..-5, and ..beta..-..beta.. bonds, to also identify characteristics of 5-5, ..beta..-1, and 4-..omicron..-5 dimers, enabled by quadrupole time-of-flight (QTOF) CID with energy-resolved mass spectrometry (ERMS). Overall, QTOFERMS offers in-depth structural information and could ultimately contribute to tools for high-throughput lignin dimer identification.
KW - collisionally activated dissociation
KW - energy-resolved mass sproctrometry
KW - lignin-derived compound characterization
UR - http://www.scopus.com/inward/record.url?scp=85142029836&partnerID=8YFLogxK
U2 - 10.1002/cssc.202201441
DO - 10.1002/cssc.202201441
M3 - Article
SN - 1864-564X
VL - 16
JO - ChemSusChem
JF - ChemSusChem
IS - 1
ER -