Fungal Cellulases

Gregg Beckham, Brandon Knott, Michael Himmel, Christina Payne, Heather Mayes, Henrik Hansson, Mats Sandgren, Jerry Ståhlberg

Research output: Contribution to journalArticlepeer-review

617 Scopus Citations


The enzymatic hydrolysis step represents the second portion of biomass depolymerization and is a major cost driver in bioethanol production due to the high cost of enzyme production. Significant efforts have been expended to understand and improve natural paradigms for enzymatic depolymerization of biomass with the aim to decrease the cost of sugar production for fuels and chemicals production. Cellulase enzyme research has been accelerated due to renewed interest in the production of ethanol from lignocellulosic biomass. Third-generation biofuels are now undergoing focused research and development with the goal of cost-effective production of infrastructure-compatible fuels from lignocellulosic biomass including fuels to fulfill demands in the gasoline, diesel, jet fuel, and maritime sectors.

Original languageAmerican English
Pages (from-to)1308-1448
Number of pages141
JournalChemical Reviews
Issue number3
StatePublished - 2015

NREL Publication Number

  • NREL/JA-5100-62519


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