Microbial Conversion of Methane

Mary Lidstrom (Inventor), Marina Kalyuzhnaya (Inventor), Derek Griffin (Inventor), Nicholas Bourdakos (Inventor), Philip Pienkos (Inventor), Lieve Laurens (Inventor)

Research output: Patent


This invention relates to a process for producing lipids and amino acids from a gaseous substrate comprising methane and oxygen. The process uses a culture of a methanotrophic microorganism in a liquid nutrient medium. The methanotrophic microorganism can be a Methylomicrobium bacterium and more specifically Methylomicrobium buryatense 5GB1. The lipid products can be in the cellular membrane of the methanotroph and can be extracted in a separate extraction zone.
Original languageAmerican English
Patent number11,220,700 B2
Filing date11/01/22
StatePublished - 2022

NREL Publication Number

  • NREL/PT-2A00-82106


  • FAEE
  • FAME
  • fatty acid ethyl esters
  • fatty acid methyl esters
  • methanotrophic microorganism


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