Optimization of C. ljungdahlii for the Valorization of Combustion Off-Gas

Matthew Lucia

Research output: NRELPresentation


One of the largest problems that faces the realization of the circular economy is the gap between waste streams and usable commodities. Synthetic biology enables a toolkit where this gap can begin to be addressed and closed. This work focuses on using synthetic biology techniques to optimize C. ljungdahlii for the valorization of combustion off-gas waste streams and navigates how to produce 3-hydroxybutyrate, a polymer precursor off of similar-composition syn-gas streams. If successful, these techniques can realize a carbon-negative solution to producing plastics.
Original languageAmerican English
Number of pages7
StatePublished - 2023

Publication series

NamePresented at the GEM Annual Board Meeting & Conference, 14-16 September 2023, Philadelphia, Pennsylvania

NREL Publication Number

  • NREL/PR-2700-87162


  • 3-hydroxybutyrate
  • Clostridium ljungdahlii
  • GEM
  • metabolic engineering
  • poly-hydroxybutyrate
  • synthetic biology


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