Oxygen-Resistant Hydrogenases and Methods for Designing and Making Same

NREL (Inventor)

Research output: Patent


The invention provides oxygen-resistant iron-hydrogenases ([Fe]-hydrogenases) for use in the production of H2. Methods used in the design and engineering of the oxygen-resistant [Fe]-hydrogenases are disclosed, as are the methods of transforming and culturing appropriate host cells with the oxygen-resistant [Fe]-hydrogenases. Finally, the invention provides methods for utilizing the transformed,oxygen insensitive, host cells in the bulk production of H2 in a light catalyzed reaction having water as the reactant.
Original languageAmerican English
Patent number7,501,270 B2
StatePublished - 2009

NREL Publication Number

  • NREL/PT-270-45830


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