Abstract
The production of lipids and astaxanthin, a high-value carotenoid, by Chlorella zofingiensis was investigated under different culture conditions. Comparative analysis revealed a good correlation between triacylglycerol (TAG) and astaxanthin accumulation in C. zofingiensis. Stress conditions promoted cell size and weight and induced the accumulation of neutral lipids, especially TAG and astaxanthin, with a concomitant decrease in membrane lipids. The highest contents of TAG and astaxanthin achieved were 387 and 4.89 mg g-1 dry weight, respectively. A semi-continuous culture strategy was developed to optimize the TAG and astaxanthin productivities, which reached 297 and 3.3 mg L-1 day-1, respectively. Additionally, astaxanthin accumulation was enhanced by inhibiting de novo fatty acid biosynthesis. In summary, our study represents a pioneering work of utilizing Chlorella for the integrated production of lipids and high-value products and C. zofingiensis has great potential to be a promising production strain and serve as an emerging oleaginous model alga.
Original language | American English |
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Pages (from-to) | 319-327 |
Number of pages | 9 |
Journal | Bioresource Technology |
Volume | 214 |
DOIs | |
State | Published - 1 Aug 2016 |
Bibliographical note
Publisher Copyright:© 2016 Elsevier Ltd.
NREL Publication Number
- NREL/JA-5100-66476
Keywords
- Astaxanthin
- Biofuels
- Chlorella zofingiensis
- Integrated production
- Stress conditions
- Triacylglycerol