Xylitol Synthesis Mutant of Xylose-Utilizing Zymomonas for Ethanol Production

Yat-Chen Chou; Paul Viitanen; Min Zhang; Caroline McCutchen

Xylitol Synthesis Mutant of Xylose-Utilizing Zymomonas for Ethanol Production

Yat-Chen Chou (Inventor)
, Paul Viitanen (Inventor)
, Min Zhang (Inventor)
, Caroline McCutchen (Inventor)

Catalytic Carbon Transformation and Scale-Up Center

National Renewable Energy Laboratory

Research output: Patent

Abstract

A strain of xylose-utilizing Zymomonas was engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation underprocess-relevant conditions.

Original language	American English
Patent number	7,741,119
State	Published - 2010

NLR Publication Number

NREL/PT-5100-51077

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Cite this

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title = "Xylitol Synthesis Mutant of Xylose-Utilizing Zymomonas for Ethanol Production",

abstract = "A strain of xylose-utilizing Zymomonas was engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation underprocess-relevant conditions.",

author = "Yat-Chen Chou and Paul Viitanen and Min Zhang and Caroline McCutchen",

year = "2010",

language = "American English",

publisher = "National Renewable Energy Laboratory (NREL)",

address = "United States",

type = "Patent",

note = "7,741,119",

}

TY - PAT

T1 - Xylitol Synthesis Mutant of Xylose-Utilizing Zymomonas for Ethanol Production

AU - Chou, Yat-Chen

AU - Viitanen, Paul

AU - Zhang, Min

AU - McCutchen, Caroline

PY - 2010

Y1 - 2010

N2 - A strain of xylose-utilizing Zymomonas was engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation underprocess-relevant conditions.

AB - A strain of xylose-utilizing Zymomonas was engineered with a genetic modification to the glucose-fructose oxidoreductase gene resulting in reduced expression of GFOR enzyme activity. The engineered strain exhibits reduced production of xylitol, a detrimental by-product of xylose metabolism. It also consumes more xylose and produces more ethanol during mixed sugar fermentation underprocess-relevant conditions.

M3 - Patent

M1 - 7,741,119

PB - National Renewable Energy Laboratory (NREL)

ER -

Xylitol Synthesis Mutant of Xylose-Utilizing Zymomonas for Ethanol Production

Abstract

NLR Publication Number

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